睾丸特异性碱性蛋白Y2抗体

英文名称    BPY2    

中文名称    睾丸特异性碱性蛋白Y2抗体    

别    名    Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.    

说 明 书    0.2ml      

研究领域    细胞生物  发育生物学  干细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500睾丸特异性碱性蛋白Y2抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    12kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BPY2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

睾丸特异性碱性蛋白Y2抗体产品介绍    background:

Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

Subunit:
Interacts with MAP1S. Interacts with UBE3A (via HECTdomain).    

睾丸特异性碱性蛋白Y2抗体

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hz-6027R CADM3/IGSF4B  细胞粘附分子3抗体

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hz-5996R CDC4/FBW7/SEL10  肿瘤抑制因子FBW7抗体

hz-5997R CADM 4  细胞粘附分子4抗体

hz-5998R DAB2IP  Dab2相互作用蛋白抗体

hz-5999R DAB2  信号转导功能磷蛋白DAB2抗体

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hz-6001R DRG1  GTP发育调控结合蛋白1抗体

hz-6002R DNAJB4/HSP40 homolog  热休克蛋白家族40抗体

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hz-6005R EXTL  外生性骨疣样蛋白2抗体

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hz-6008R GADD45GIP1  GADD45γ相互作用蛋白1抗体

hz-6009R GAS8  生长停滞特异性蛋白8抗体

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