p60TRP蛋白抗体

英文名称    BHLHB9/p60TRP    

中文名称    p60TRP蛋白抗体    

别    名    Basic helix loop helix domain containing class B 9; BHLHB 9; bHLHB9; KIAA1701; p60 like protein; p60TRP; Protein BHLHb9; Transcription regulator of 60 kDa; BHLH9_HUMAN .    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  神经生物学  Alzheimer's      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 p60TRP蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    60kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BHLHB9/p60TRP (451-547aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

p60TRP蛋白抗体产品介绍    background:

Basic helix-loop-helix (bHLH) proteins are a group of transcription factors that influence the regulation of neurogenesis, cardiogenesis, myogenesis, differentiation and cell proliferation. p60TRP (p60-transcription-regulator-protein), also known as BHLHb9 (basic helix-loop-helix domain containing, class B, 9) or p60-like protein, is a 547 amino acid cytoplasmic and nuclear protein that belongs to the GPRASP family. A few members of the GRASP family are considered G protein-coupled receptors that play a role in many different stimulus-response pathways. Highly expressed in brain, p60TRP may be involved in the control of cellular aging and survival. In colon cancer cells, p60TRP is down regulated due to CpG hypermethylation of its promoter, and patients suffering from Alzheimer disease have low levels of p60TRP. p60TRP binds to karyopherin ∫3, also known as Ran BP-5, and protein-phosphatase-2A (PP2A), and is encoded by a gene located on human chromosome Xq22.1.

Function:
BHLHB9, or basic helix loop helix domain containing, class B 9, interacts with the Ran-binding-protein-5 (RanBP5) and the protein-phosphatase-2A (PP2A). It can also affect NNT1 and p48ZnF signaling and is down-regulated in the brain of AD subjects. Thus BHLHB9 may have a possible pivotal role in the control of cellular aging and survival. Hypermethylation of the BHLHB9 gene occurs in premalignant lesions and accumulates during tumorigenesis.    

p60TRP蛋白抗体

hz-1386 AT II R1(Human angiotension II receptor 1 Antibody) ELISA Kit  人血管紧张素Ⅱ受体1抗体

hz-1387 C1INH(Mouse Complhzent 1 inhibitor autoantibody) ELISA Kit  小鼠补体1抑制物抗体

hz-1387 ANG- I R(Human angiotension I receptor Antibody) ELISA Kit  人血管紧张素Ⅰ受体抗体

hz-1387 Gelsolin ELISA Kit  大鼠凝溶胶蛋白

hz-1388 PABA(Mouse para-aminobenzoic acid) ELISA Kit  小鼠对氨基苯甲酸

hz-1388 OVA sIgG(Human ovalbumin specific IgG) ELISA Kit  人卵清蛋白特异性IgG

hz-1388 RANKL ELISA Kit  大鼠核因子κB受体活化因子配基

hz-1389 CAM-ab(Human anti-calmodulin specific antibody) ELISA Kit  人抗钙调素特异抗体

hz-1389 TpP ELISA Kit  大鼠血栓前体蛋白

hz-1389 hs-CRP(Mouse high sensitivity C-Reactive Protein) ELISA Kit  小鼠超敏C反应蛋白

hz-1390 Beta2-GP1 IgA/G/M(Mouse Beta2-glycoprotein 1 antibody IgA/G/M) ELISA Kit  小鼠β2糖蛋白1抗体IgA/G/M

hz-1390 INH-B ELISA Kit  大鼠抑制素B

hz-1390 THAA(Human thyroid hormone autoantibodies) ELISA Kit  人甲状腺非肽激素抗体

hz-1391 LAT(Mouse Linker for activation of T cell) ELISA Kit  小鼠T细胞活化连接蛋白

hz-1391 SCA(Human steroid producing cell autoantibody) ELISA Kit  人抗类固醇生成细胞抗体

hz-1391 ISR- Beta ELISA Kit  大鼠胰岛素受体β

hz-1392 GHbA1c ELISA Kit  大鼠糖化血红蛋白A1c

hz-1392 GS-ANA(Human granulocyte specific antinuclear antibody) ELISA Kit  人粒细胞特异性抗核抗体

hz-1392 hzAb(Mouse Endometrium Antibody) ELISA Kit  小鼠抗子宫内膜抗体

hz-1393 LDL-IC(Mouse LDL-IC) ELISA Kit  小鼠低密度脂蛋白免疫复合物

hz-1393 LFA-3/CD58 ELISA Kit  大鼠淋巴细胞功能相关抗原3

hz-1393 SRP(Human signal recognization particle antibody) ELISA Kit  人抗信号识别颗粒抗体

hz-1394 BA(Human Blocking antibody) ELISA Kit  人封闭抗体

hz-1394 UU-Ab(Mouse Ureaplasma urealyticum antibody) ELISA Kit  小鼠解脲脲原体抗体

hz-1394 sPECAM-1/sCD31 ELISA Kit  大鼠可溶性血小板内皮细胞粘附分子1

hz-1395 cmDNA(Human anti-cell mhzbrane DNA antibody) ELISA Kit  人抗细胞膜DNA抗体

hz-1395 MHC III /AgB III /H-1 III ELISA Kit  大鼠主要组织相容性复合体Ⅲ类

hz-1395 GFAP(Mouse glial fibrillary acidic protein) ELISA Kit  小鼠神经胶质纤维酸性蛋白

hz-1396 ACAST-D IV (Human autoantibodies against the C-terminal domain IV ) ELISA Kit  人抗钙蛋白酶抑素抗体