英文名称 BCA2
中文名称 乳腺癌相关基因2抗体(锌指蛋白364)
别 名 BCA2; Breast cancer associated gene 2; CL469780; Rabring 7; RING finger protein 115; RNF115; Zinc finger protein 364; ZNF364; ZNF 364; RN115_HUMAN.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 细胞类型标志物 肿瘤细胞生物标志物 锌指蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 乳腺癌相关基因2抗体(锌指蛋白364)(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF364/BCA2/RNF115
亚 型 IgG
纯化方法 affinity purified by Protein A 乳腺癌相关基因2抗体(锌指蛋白364)
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.
Function:
Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
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