BCL2分子伴侣调节蛋白5抗体

英文名称    BAG5    

中文名称    BCL2分子伴侣调节蛋白5抗体    

别    名    BAG family molecular chaperone regulator 5; BAG 5; BAG-5; BCL2 associated athanogene 5; KIAA0873; BAG5_HUMAN.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 BCL2分子伴侣调节蛋白5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    51kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BAG5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

BCL2分子伴侣调节蛋白5抗体产品介绍    background:

BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70’s anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Function:
Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.     

BCL2分子伴侣调节蛋白5抗体公司更多热销抗体产品如下：

hz-0368G-RBIThz Goat Anti-Mouse IgM/RBITC  罗丹明标记的羊抗小鼠IgM

hz-0368G-FIThz Goat Anti-Mouse IgM/FITC  FITC标记的羊抗小鼠IgM

hz-0368G-hzy3 Goat Anti-Mouse IgM/Cy3  Cy3标记的羊抗小鼠IgM

hz-0368G-hzy5 Goat Anti-Mouse IgM/Cy5  Cy5标记的羊抗小鼠IgM

hz-0368G-hzy5.5 Goat Anti-Mouse IgM/Cy5.5  Cy5.5标记的羊抗小鼠IgM

hz-0368G-hzy7 Goat Anti-Mouse IgM/Cy7  Cy7标记的羊抗小鼠IgM

hz-0368G-PE Goat Anti-Mouse IgM/PE  PE标记的羊抗小鼠IgM

hz-0368G-PE-hzy3 Goat Anti-Mouse IgM/PE-Cy3  PE-Cy3标记的羊抗小鼠IgM

hz-0368G-PE-hzY5 Goat Anti-Mouse IgM/PE-CY5  PE-CY5标记的羊抗小鼠IgM

hz-0368G-APhz Goat Anti-Mouse IgM/APC  APC标记的羊抗小鼠IgM

hz-0368G-AF350 Goat Anti-Mouse IgM/Alexa Fluor 350  Alexa Fluor 350标记的羊抗小鼠IgM

hz-0368G-AF488 Goat Anti-Mouse IgM/Alexa Fluor 488  Alexa Fluor 488标记的羊抗小鼠IgM

hz-0368G-AF555 Goat Anti-Mouse IgM/Alexa Fluor 555  Alexa Fluor 555标记的羊抗小鼠IgM

hz-0368G-AF647 Goat Anti-Mouse IgM/Alexa Fluor 647  Alexa Fluor 647标记的羊抗小鼠IgM

hz-0368G-PE-hzy5.5 Goat Anti-Mouse IgM/PE-Cy5.5  PE-Cy5.5标记的羊抗小鼠IgM

hz-0368G-PE-hzy7 Goat Anti-Mouse IgM/PE-Cy7  PE-Cy7标记的羊抗小鼠IgM

hz-0368G-AP Goat Anti-Mouse IgM/AP  碱性磷酸酶（AP）标记的羊抗小鼠IgM

hz-0368G-Gold Goat Anti-Mouse IgM/Gold  胶体金标记的羊抗小鼠IgM

hz-0368G-Bio Goat Anti-Mouse IgM/Bio  生物素标记的羊抗小鼠IgM

hz-0368G-HRP Goat Anti-Mouse IgM/HRP  辣根过氧化物酶标记的羊抗小鼠IgM

hz-0293G-hzy3 Goat Anti-rat IgG/Cy3  Cy3标记的羊抗大鼠IgG

hz-0293G-hzy5 Goat Anti-rat IgG/Cy5  Cy5标记的羊抗大鼠IgG

hz-0293G-hzy5.5 Goat Anti-rat IgG/Cy5.5  Cy5.5标记的羊抗大鼠IgG

hz-0293G-hzy7 Goat Anti-rat IgG/Cy7  Cy7标记的羊抗大鼠IgG

hz-0293G-PE Goat Anti-rat IgG/PE  PE标记的羊抗大鼠IgG

hz-0293G-PE-hzy3 Goat Anti-rat IgG/PE-Cy3  PE-Cy3标记的羊抗大鼠IgG

hz-0293G-PE-hzY5 Goat Anti-rat IgG/PE-CY5  PE-CY5标记的羊抗大鼠IgG

hz-0293G-APhz Goat Anti-rat IgG/APC  APC标记的羊抗大鼠IgG

hz-0293G-AF350 Goat Anti-rat IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗大鼠IgG

hz-0293G-AF488 Goat Anti-rat IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗大鼠IgG

hz-0293G-PE-hzy5.5 Goat Anti-rat IgG/PE-Cy5.5  PE-Cy5.5标记的羊抗大鼠IgG

hz-0293G-PE-hzy7 Goat Anti-rat IgG/PE-Cy7  PE-Cy7标记的羊抗大鼠IgG

hz-0293G-Bio Goat Anti-rat IgG/Bio  生物素标记的羊抗大鼠IgG

hz-0293G-RBIThz Goat Anti-rat IgG/RBITC  罗丹明标记的羊抗大鼠IgG

hz-0293G-AP Goat Anti-rat IgG/AP  碱性磷酸酶（AP）标记的羊抗大鼠IgG

hz-0293G-Gold Goat Anti-rat IgG/Gold  胶体金标记的羊抗大鼠IgG