骨形态发生蛋白4抗体

英文名称    BMP4    

中文名称    骨形态发生蛋白4抗体    

别    名    BMP 4; BMP2B; BMP2B1; Bone morphogenetic protein 4; DVR4; ZYME; BMP4_HUMAN; BMP-4; Bone morphogenetic protein 2B; BMP-2B.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 骨形态发生蛋白4抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    13/45kDa    

细胞定位    细胞外基质 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BMP4    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

骨形态发生蛋白4抗体产品介绍    background:

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Function:
Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).    

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hz-1829R IL-15  白介素15抗体

hz-1830R IL-16  白介素16抗体

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hz-2461R IL-13Ra2  白细胞介素-13受体a2抗体

hz-0768R IL-16/LCF  白介素-16抗体

hz-1183R IL-17A  白介素-17抗体

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hz-2606R IL-17R/IL-17RA/CD217  白介素17受体抗体

hz-2607R IL-17RC/IL-17RL  白介素17受体C抗体

hz-2608R IL-17RD  白介素17受体D抗体

hz-2609R IL-17B  白介素-17B抗体

hz-2610R IL-17RB  白介素-17B受体抗体

hz-2611R IL-17C  白介素-17C抗体

hz-2612R IL-17D/IL-27  白介素-17D抗体

hz-2613R IL-17E/IL-25  白介素-17E抗体

hz-2614R IL-17F/IL-24  白介素-17F抗体

hz-2711R IL-27R/TCCR  白细胞介素27受体抗体

hz-0529R IL-18/IGIF  白细胞介素-18/干扰素γ诱导因子抗体

hz-4040R IL18BP  白细胞介素18结合蛋白抗体

hz-2615R IL-18R alpha/CD218a  白细胞介素-18受体α链抗体