Bcl-2同源结构域蛋白抗体

英文名称    Beclin 1    

中文名称    Bcl-2同源结构域蛋白抗体    

别    名    Beclin 1; ATG6; beclin1; VPS30; Beclin 1 like protein 1; 4921513J16Rik; 5430417M23Rik; ATG6; BECLIN 1; BECN1; MGC6843; BECN1_HUMAN.    

说 明 书    0.1ml  0.2ml  1ml    

研究领域    肿瘤  免疫学  神经生物学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 Bcl-2同源结构域蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    50kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BECN1 (236-280aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

Bcl-2同源结构域蛋白抗体产品介绍    background:

Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.

Function:
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.    

Bcl-2同源结构域蛋白抗体公司更多热销抗体产品如下：

hz-1156R NFKBIB/IKB beta  核因子κB抑制蛋白β抗体

hz-3191R Phospho-NFKBIB (Ser23)   磷酸化KB抑制蛋白β抗体

hz-1287R NFKBIA/IKB alpha  核因子κB抑制蛋白α抗体

hz-3229R IKKα(Phospho-Thr23)  磷酸化KB抑制蛋白激酶α抗体

hz-3234R phospho-IKK alpha (Tyr463)  磷酸化KB抑制蛋白激酶α抗体

hz-3235R phospho-IKK alpha (Ser176 + Ser180)  磷酸化KB抑制蛋白激酶α抗体

hz-3236R Phospho-IKK alpha/IKK beta (Ser180/Ser181)  磷酸化KB抑制蛋白激酶α/β抗体

hz-3237R Phospho-IKK alpha/beta (Ser176/Ser180)  磷酸化KB抑制蛋白激酶α/β抗体

hz-2513R phospho-NFKBIA(Ser32/36)  磷酸化IKB alpha(Ser32/36)抗体

hz-3233R phospho-IKK beta(Tyr188)  磷酸化KB抑制蛋白激酶β抗体

hz-3231R phospho-IKK beta(Ser466)  磷酸化KB抑制蛋白激酶β抗体

hz-3232R phospho-IKK beta(Tyr199)  磷酸化KB抑制蛋白激酶β抗体

hz-5514R Phospho-NFKBIA (Tyr42)   磷酸化IKB α抗体

hz-5398R phospho-IKK beta(Ser471)  磷酸化KB抑制蛋白激酶β抗体

hz-5399R phospho-IKK beta(Ser740)  磷酸化KB抑制蛋白激酶β抗体

hz-5515R phospho-NFKBIA(Tyr305)  磷酸化IKB alpha抗体

hz-5440R phospho-IKK beta(Ser733)  磷酸化KB抑制蛋白激酶β抗体

hz-5441R phospho-IKK beta(S474)  磷酸化KB抑制蛋白激酶β抗体

hz-5442R phospho-IKK beta(Ser476)  磷酸化KB抑制蛋白激酶β抗体

hz-3227R phospho-IKK gamma (Ser85)  磷酸化KB抑制蛋白激酶γ抗体

hz-3228R phospho-IKK gamma (Ser31)  磷酸化KB抑制蛋白激酶γ抗体

hz-3230R phospho-IKK gamma (Ser376)  磷酸化KB抑制蛋白激酶γ抗体

hz-5393R phospho-IKK gamma(Ser43)  磷酸化KB抑制蛋白激酶γ抗体

hz-4114R IKBKE/IKKi  核因子κB抑制蛋白E抗体

hz-5454R phospho-IKBKE(Thr501)  磷酸化核因子κB抑制蛋白E抗体

hz-5517R phospho-NFKBIE (Ser157)  磷酸化KB抑制蛋白激酶ε

hz-0245R IKI3 family protein  拟南芥IKI3抗体

hz-2428R IL-9  白介素9抗体

hz-0698R IL-10  白细胞介素-10抗体

hz-1827R IL-11  白介素11抗体