乳腺癌易感基因2抗体

英文名称    FANCB/BRCA2    

中文名称    乳腺癌易感基因2抗体    

别    名    BRCA 2; BRCA1/BRCA2 containing complex subunit 2; BRCC 2; BRCC2; Breast and ovarian cancer susceptibility gene early onset; Breast cancer 2 early onset; Breast Cancer 2 tumor suppressor; Breast cancer susceptibility protein BRCA2; Breast cancer type 2 susceptibility protein; FACD; FAD 1; FAD; FAD1; FANCB; FANCD 1; FANCD; FANCD1; Fanconi anemia complementation group D1; Fanconi anemia group D1 protein; OTTHUMP00000018803; OTTHUMP00000042401.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,     

乳腺癌易感基因2抗体产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    384kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BRCA2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

乳腺癌易感基因2抗体产品介绍    background:

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Function:
Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. In concert with NPM1, regulates centrosome duplication.    

乳腺癌易感基因2抗体公司更多热销抗体产品如下：

hz-0136R GTP cyclohydrolase 1/GTP-CH-1  三磷酸鸟苷环水解酶抗体

hz-2516R GTSE-1  G2期/S期应答相关蛋白1抗体

hz-3990R GYG1  糖原蛋白1抗体

hz-3991R GYG2  糖原蛋白2抗体

hz-5064R LCHAD/HADHA  长链烯脂酰辅酶A脱氢酶抗体

hz-5065R HADHB  羟辅酶A脱氢酶β抗体

hz-0344R H5N1 Matrix Protein 2  A型禽流感病毒H5N1-M2蛋白抗体

hz-1430R H1N1 matrix protein 2  甲型流感病毒M2抗体

hz-2284R H5N1 Hhzagglutinin  A型流感病毒H5N1凝集素

hz-2285R H5N1 Hhzagglutinin  A型流感病毒H5N1凝集素抗体

hz-4543R H9N1 Hhzagglutinin  A型流感病毒H9N1血凝素型抗体

hz-4552R H1N1 Matrix Protein 1  A型禽流感病毒H1N1蛋白抗体

hz-0422R H1N1 Matrix Protein 2/Influenza A bp1   A型猪流感病毒H1N1-M2蛋白抗体

hz-2001R H1N1 Hhzagglutinin 1/Influenza A bp1  甲型流感病毒血凝素抗体

hz-4544R H9N1 Neuraminidase  A型流感病毒H9N1神经氨酸酶型抗体

hz-2002R H1N1 Hhzagglutinin 1/HA probe  甲型流感病毒血凝素抗体

hz-1690R H2N2 Hhzagglutinin  甲型流感病毒血凝素抗体（H2N2）

hz-3779R Histone H2A  组蛋白H2A抗体

hz-3781R Acetyl-Histone H2A(K5)  乙酰化组蛋白H2A抗体

hz-2560R Histone H2A.x  组蛋白H2AX抗体

hz-3185R Phospho-Histone H2A.X (Ser139)  磷酸化组蛋白H2AX抗体

hz-5360R Phospho-Histone H2A.X (Tyr143)  磷酸化组蛋白H2AX抗体

hz-3652R Histone H2B  组蛋白H2B抗体

hz-3782R Acetyl-Histone H2B(K5)  乙酰化组蛋白H2B抗体

hz-3783R Acetyl-Histone H2B(K20)  乙酰化组蛋白H2B抗体

hz-2003R H1N1 Hhzagglutinin 2  甲型流感病毒血凝素抗体

hz-2004R H1N1 Hhzagglutinin 2  甲型流感病毒血凝素抗体

hz-4619R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-4620R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-4621R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-5888R Hyaluronidase2  透明质酸酶2/玻璃酸酶2抗体