英文名称 Bcl-2
中文名称 Bcl-2抗体
别 名 Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 细胞凋亡 肿瘤细胞生物标志物 新陈代谢
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 Bcl-2抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞核 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bcl-2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Bcl-2抗体产品介绍 background:
The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).
Function:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Bcl-2抗体公司更多热销抗体产品如下:
hz-5770R FGF17 成纤维细胞生长因子17抗体
hz-5771R FGF19 成纤维细胞生长因子19抗体
hz-5772R FGF20 成纤维细胞生长因子20抗体
hz-1768R FGFBP 纤维细胞生长因子结合蛋白抗体
hz-5773R FGF22 成纤维细胞生长因子22抗体
hz-2318R FGF21 成纤维细胞生长因子21抗体
hz-0230R bFGFR/FGFR1 碱性成纤维细胞生长因子受体1抗体
hz-5938R DAT1/LIM domain only 3 神经细胞特异性转录因子DAT1抗体
hz-3205R Phospho-FGFR1(Tyr653/654) 磷酸化碱性成纤维细胞生长因子受体1抗体
hz-3136R Phospho-FGFR1 (Tyr766) 磷酸化碱性成纤维细胞生长因子受体1抗体
hz-5325R Phospho-FGFR1 (Tyr307) 磷酸化碱性成纤维细胞生长因子受体1抗体
hz-5326R Phospho-FGFR1+FGFR2 (Tyr463) 磷酸化碱性成纤维细胞生长因子受体1抗体
hz-5936R MOS 原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体
hz-0675R FGFR2/CD332 成纤维细胞生长因子受体2抗体
hz-1301R FGFR3/CD333 成纤维细胞生长因子受体3抗体
hz-0676R FGFR4/CD334 成纤维细胞生长因子受体4抗体
hz-5939R PBOV1 前列腺癌和乳腺癌高表达蛋白抗体
hz-6049R FGFR5/FGFRL1 成纤维细胞生长因子受体5抗体
hz-5712R FGFR1OP/FOP 成纤维细胞生长因子受体1原癌基因伴侣蛋白抗体
hz-5768R FGF23 成纤维细胞生长因子23抗体
hz-0315R FGL2 凝血酶原酶(纤维介素)抗体
hz-5940R RAD54B DNA修复和重组蛋白RAD54B抗体
hz-0809R Fibulin 1 “衰老关键蛋白”抗体
hz-5941R RRAS2 畸胎瘤癌基因RAS相关病毒抗体
hz-0810R Fibulin 5 衰老关键蛋白抗体
hz-1240R human Fibrinogen 人纤维蛋白原抗体
hzm-1240M human Fibrinogen Monoclonal 人纤维蛋白原单克隆抗体
hz-3998R Fibrillarin 核仁纤维蛋白抗体
hz-3657R FLASH/CASP8AP2 半胱氨酸蛋白酶8相关蛋白2抗体
hz-1462R FLG 丝聚合蛋白/中间丝蛋白抗体
hz-0119R FLIP/c FLIP 凋亡调节基因之一抗体
更多
企业名称
上海沪震生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001371133
成立日期
2014-05-08
注册资本
1000
经营范围
上海沪震生物科技有限公司
公司地址
上海市杨浦区密云路1018号复旦科技园808室
客服电话