遗传性失明相关蛋白AIPL1抗体

英文名称    AIPL1    

中文名称    遗传性失明相关蛋白AIPL1抗体    

别    名    A930007I01Rik; Aipl1; AIPL1_HUMAN; AIPL2; Aryl hydrocarbon interacting protein like 1; Aryl hydrocarbon receptor interacting protein like 1; Aryl-hydrocarbon-interacting protein-like 1; LCA4; MGC25485; OTTHUMP00000128207; OTTMUSP00000006382; RP23-401C17.1.    

说 明 书    0.1ml      

研究领域    细胞生物  神经生物学  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 遗传性失明相关蛋白AIPL1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    44kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human AIPL1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

遗传性失明相关蛋白AIPL1抗体产品介绍    background:

The inherited blindness associated protein, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), interacts with the cell cycle regulator protein NUB1. AIPL1 is crucial for protein folding and stabilization, as well as for protein trafficking. It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina. In the retina, AIPL1 is expressed in both developing cone and rod photoreceptors, but it is restricted to rod photoreceptors in the adult human retina. Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, an early-onset, inherited autosomal recessive disorder that results in childhood blindness.

Function:
May be important in protein trafficking and/or protein folding and stabilization.    

遗传性失明相关蛋白AIPL1抗体公司更多热销抗体产品如下：

hz-0633R CDK4  周期素依赖性激酶4抗体

hz-4299R CNTROB  乳腺癌易感基因2相互作用蛋白抗体

hz-5727R HEC1  癌细胞高表达蛋白Hec1抗体

hz-0559R CDK5  周期素依赖性激酶5抗体

hz-5728R HURP/DAP5  肝癌上调蛋白抗体

hz-0568R CDK6  周期素依赖性激酶6抗体

hz-5286R phospho-CDK6 (Tyr13)  磷酸化周期素依赖性激酶6抗体

hz-5287R phospho-CDK6 (Tyr24)  磷酸化周期素依赖性激酶6抗体

hz-0569R CDK7  周期素依赖性激酶7抗体

hz-5729R LGALS3BP  可溶性半乳糖凝集素3结合蛋白抗体

hz-5248R phospho-CDK7 (Thr170)  磷酸化周期素依赖性激酶7抗体

hz-5730R MAD2  有丝分裂阻滞缺陷蛋白2抗体

hz-0570R CDK8  周期素依赖性激酶8抗体

hz-1388R CDK9/Cyclin T1  周期素依赖性激酶9抗体

hz-3097R Phospho-CDK9 (Thr186)  磷酸化周期素依赖性激酶9抗体

hz-5249R Phospho-CDK9 (Thr29)  磷酸化周期素依赖性激酶9抗体

hz-2361R CDK10  周期素依赖性激酶10

hz-3999R CDK11  周期素依赖性激酶11抗体

hz-0538R CDKN1C/p57 Kip2  周期蛋白依赖激酶抑制因子1C抗体

hz-5731R Mad2L1  有丝分裂阻滞缺陷2样蛋白1抗体

hz-3713R Phospho-p57 Kip2 (Thr310)  磷酸化周期蛋白依赖激酶抑制因子1C抗体

hz-5732R NEK2  中心体相关蛋白激酶Nek2抗体

hz-1093R CGP-39/YKL-40  软骨糖蛋白39抗体

hz-0060R CEA/CD66e/CEACAM5  癌胚抗原抗体

hz-5733R PAR6  缺陷性分配同源物α抗体

hz-0719R CEA  癌胚抗原抗体

hzm-1623M CEA(C3)  癌胚抗原单克隆抗体（包被）

hzm-1624M CEA(B5)  癌胚抗原单克隆抗体（检测）

hz-5734R PCGF1  表观抑制因子Polycomb家族成员PCGFl蛋白抗体