磷酸化CD156b抗体

英文名称    phospho-ADAM17 (Thr735)    

中文名称    磷酸化CD156b抗体    

别    名    ADAM17 (phospho T735); p-ADAM17 (phospho T735); p-CD156b(phospho T735); A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme).    

说 明 书    0.1ml  0.2ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  细胞生物  神经生物学  信号转导  干细胞  转录调节因子  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500磷酸化CD156b抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    68kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human ADAM17 around the phosphorylation site of Thr735    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化CD156b抗体产品介绍    background:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].

Function:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity).     

磷酸化CD156b抗体公司更多热销抗体产品如下：

hz-4914R CD8B  CD8β链（CD8-β）抗体

hz-4602R CD8/CD8-β  CD8抗体

hz-2489R CD9/MRP-1  CD9蛋白抗体

hz-5711R CCDC106  卷曲螺旋结构域蛋白106抗体

hz-2929R CD40/TNFRSF5  肿瘤坏死因子受体超家族成员5抗体

hz-1286R CD40L  CD40L抗体

hz-2347R GP1B/CD42b  血小板糖蛋白GPIb抗体

hz-2636R Integrin alpha 2b/CD41  血小板膜糖蛋白ⅡbⅢa抗体

hz-2496R CD43/SPN  CD43抗体

hz-0521R CD44/HCAM/PGP1  CD44抗体

hz-4281R HAUSP/USP7  疱疹病毒相关泛素特异性蛋白酶7抗体

hz-2783R CD44v4  CD44V4抗体

hz-2782R CD44v5  CD44V5抗体

hz-2507R CD44v6  CD44V6抗体

hz-2779R CD44v7  CD44V7抗体

hz-2780R CD44v10  CD44V10抗体

hz-5713R HOXA5  同源异型盒基因HOXA5蛋白抗体

hz-5714R OVCA1  卵巢癌相关基因1抗体

hz-0522R CD45/B220  白细胞共同抗原抗体

hz-1529R CD46/MCP (human)  膜辅蛋白抗体（人）

hz-1539R CD46/MCP  膜辅蛋白抗体

hz-1708R CD45RO  CD45RO抗体

hz-2386R CD47/MER6  整合素相关蛋白CD47

hz-2497R CD48/SLAMF2  CD48抗体

hz-2498R CD58/LFA-3  淋巴细胞功能相关抗原-3抗体

hz-5715R RPL11/GIG34  细胞生长抑制蛋白34

hz-2635R Integrin alpha 2/CD49b  整合素α2抗体

hz-3793R CD75  唾液酸转移酶1/α-2,6唾液酸转移酶抗体

hz-1113R CD5  CD5抗体

hz-5716R ZNF693/CASZ1  锌指蛋白693抗体