英文名称 ASCL2
中文名称 ASCL2蛋白抗体
别 名 Achaete scute complex like 2; Achaete scute homolog 2; achaete-scute complex-like 2; Achaete-scute homolog 2; ASCL2; ASCL2_HUMAN; ASH-2; Ash2; bHLHa45; Class A basic helix-loop-helix protein 45; HASH2; Mash2.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 发育生物学 信号转导 干细胞 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 ASCL2蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Human ASCL2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ASCL2蛋白抗体产品介绍 background:
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. ASCL2 is a 193 amino acid protein that localizes to the nucleus and contains one bHLH domain. Expressed in developing placental tissue, ASCL2 binds to DNA and functions as a transcriptional regulator that is involved in the maturation of neuronal precursors in the peripheral and central nervous systems.
Function:
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
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企业名称
上海沪震生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001371133
成立日期
2014-05-08
注册资本
1000
经营范围
上海沪震生物科技有限公司
公司地址
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