英文名称 AKR7A2
中文名称 醛固酮类还原酶家族7成员A2抗体
别 名 AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1 AR1; AFB1-AR 1; AFB1AR1; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase member 2; Aflatoxin beta1 aldehyde reductase; Aiar; AKR7; Akr7a2; Aldo keto reductase family 7; Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase; Aldo keto reductase family 7 member A2; Aldoketoreductase 7; ARK72_HUMAN; SSA reductase; SSA reductase; Succinic semialdehyde reductase.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 神经生物学 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500醛固酮类还原酶家族7成员A2抗体 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKR7A2 (81-150aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
醛固酮类还原酶家族7成员A2抗体产品介绍 background:
The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.
Function:
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
醛固酮类还原酶家族7成员A2抗体公司更多热销抗体产品如下:
hz-0923P Pdx1(pancreatic and duodenal homeobox 1) 胰十二指肠同源异型盒基因抗原
hz-2219P pectinesterase inhibitor 18 peptide 果胶酶抗原
hz-1084P PEG10(Paternally expressed gene 10) 肝癌高表达基因抗原
hz-2106P PENK/Enkephalin A(Preproencephalin A) 脑啡肽
hz-0584P PEPT2 (Peptide-transporters 2) 肠道肽转运蛋白2/小肽转运蛋白2抗原
hz-2469P PERK(PRKR-like endoplasmic reticulum kinase) 蛋白激酶R样内质网激酶抗原
hz-0796P FSCN1 (Fascin 1 protein; fascin homolog 1, actin-bundling protein) 纤维束蛋白同源物1/肌动蛋白集束蛋白/圆线虫紫癜 抗原
hz-0563P P-GP(P-glycoprotein) P-糖蛋白抗原
hz-1551P Pepsinogen C peptide 胃蛋白酶原C蛋白抗原
hz-1832P PGC-1 Alpha(peroxisome proliferator-activated receptor- Gamma coactivator 1 Alpha) 过氧化物酶体增殖物激活受体γ辅激活子1α抗原
hz-0823P PGRN (progranulin) 颗粒蛋白前体抗原
hz-1449P PHB(Prohibitin) 抑制素/肿瘤抑制因子抗原
hz-0520P PKA(Protein Kinase A) 蛋白激酶A(多肽)
hz-1098P PLAU/uPA (Plasminogen activator,urokinase) 尿激酶型纤溶酶原激活因子(多肽)
hz-1048P Podoplanin Protein 平足蛋白抗原
hz-0891P Pokhzon (POK Erythroid Myeloid Ontogenic factor) “扑克蒙”蛋白又称“波克曼”蛋白
hz-2157P Polycystin 1(Polycystic Kidney Disease 1) 多囊肾蛋白1抗原
hz-2158P Polycystin 2(polycystic kidney disease 2) 多囊肾蛋白2抗体
hz-0876P phospho-AKT1/PKB1/2/3(pThr473)peptide 磷酸化蛋白激酶B抗原(丝氨酸磷酸化位点:473)
hz-1436P RKIP(Raf kinase inhibitor protein) Raf激酶抑制蛋白抗原
hz-2146P pre-X protein[Hepatitis B virus]N-Terminus 乙肝病毒pre-X蛋白抗原(N端)
hz-2147P pre-X protein(CT)[Hepatitis B virus C-Terminus] 乙肝病毒pre-X蛋白抗原(C端)
hz-0532P PHD3 (Egln3; HIF-prolyl hydroxylase 3) 脯氨酸羟化酶(多肽)
hz-0433P ADAMTS-7(a disintegrin-like and metalloprotease-7 ) 新型金属基质蛋白酶(抗原)
醛固酮类还原酶家族7成员A2抗体信息由上海沪震生物科技有限公司为您提供,如您想了解更多关于醛固酮类还原酶家族7成员A2抗体报价、型号、参数等信息,欢迎来电或留言咨询。除供应醛固酮类还原酶家族7成员A2抗体外,上海沪震生物科技有限公司还可为您提供cdc25C (Ab-216) 抗体、JAK2 (Ab-1007) 抗体、IκB-α (Ab-32/36) 抗体等产品,公司有专业的客户服务团队,是您值得信赖的合作伙伴。