精氨酸酶2抗体

英文名称    Arginase II    

中文名称    精氨酸酶2抗体    

别    名    ARG 2; ARG2; ARGI2_HUMAN; Arginase2; Arginase liver; Arginase type II; Arginase II; ArginaseII; Arginase-II; Arginase1.    

说 明 书    0.1ml      

研究领域    肿瘤  细胞生物  信号转导  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 精氨酸酶2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    36kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Arginase II    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

精氨酸酶2抗体产品介绍    background:

Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea (1). The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster (2-4). Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location (5,6). Specifically, arginase II localizes to the mitochondria (5,6). Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver (5,6). The human arginase II gene, which maps to chromosome 14q24.1, encodes a 354 amino acid protein (3,5-7). In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence (5,6).

Function:
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.    

精氨酸酶2抗体公司更多热销抗体产品如下：

hz-9998R C4orf44  4号染色体开放阅读框44抗体

hz-9999R C5ORF33  5号染色体开放阅读框33抗体

hz-10031R Kappa-casein/CSN3  κ-酪蛋白抗体

hz-10032R Beta-casein  β-酪蛋白抗体

hz-10033R Alpha s1 Casein  α-s1酪蛋白抗体

hz-10034R Alpha s2 Casein  α-s2酪蛋白抗体

hz-4233R DRAM  DNA损伤自噬调整蛋白抗体

hz-0634R AQP4  水通道蛋白-4抗体

hz-1554R AQP5  水通道蛋白5抗体

hz-2506R AQP7  水通道蛋白-7抗体

hz-4234R ABAT  γ氨基丁酸转氨酶抗体

hz-2060R AQP9  水通道蛋白-9抗体

hz-0118R Androgen receptor  雄激素受体抗体

hz-5178R Chondroitin Sulfate  硫酸软骨素抗体

hz-0943R phospho-Androgen Receptor(Ser580)  磷酸化雄激素受体抗体

hz-3004R phospho-Androgen Receptor(Ser595)  磷酸化雄激素受体抗体

hz-2903R ARHI  抑癌基因ras同源家族1抗体

hz-5191R phospho-Androgen Receptor (Ser212)  磷酸化雄激素受体抗体

hz-3847R Amphiregulin  双调蛋白（结肠直肠细胞源性生长因子）抗体

hz-2405R AKR1B1  醛糖还原酶抗体

hz-3751R ARA24  雄激素受体相关蛋白24抗体

hz-5192R phospho-Androgen Receptor(Ser660)  磷酸化雄激素受体抗体

hz-0385R ARC/Arg3.1  ARC抗体

hz-1145R ARF6  ADP核糖基化因子6抗体

hz-1477R Arfaptin 1  ADP核糖基化因子结合蛋白1抗体

hz-4230R mSin3A  同源转录调节蛋白Sin3A抗体

hz-1442R Arfaptin 2  ADP核糖基化因子结合蛋白2抗体

hz-3006R phospho-arfaptin 2(Ser260)  磷酸化ADP核糖基化因子结合蛋白2抗体