英文名称 AE2
中文名称 阴离子交换蛋白2抗体
别 名 AE 2; AE-2; AE2 anion exchanger; Anion exchange protein 2; Anion exchanger 2; B3A2_HUMAN; BND3L; EPB3L1; HKB3; MPB3L; Non-erythroid band 3-like protein; SLC4A2; Solute carrier family 4 member 2.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 心血管 细胞生物 通道蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 阴离子交换蛋白2抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 137kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AE2/SLC4A2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
阴离子交换蛋白2抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors, including hormones, innervation/neuropeptides and biliary constituents. The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow. Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange. The AE2 protein regulates pH, chloride concentration, cell volume and transepithelial ion transport in many tissues. Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis.
Function:
Plasma membrane anion exchange protein of wide distribution.
阴离子交换蛋白2抗体公司更多热销抗体产品如下:
hz-8523R TET1/CXXC6 Ten-eleven转运基因1蛋白抗体
hz-8524R Calcium Sensing Receptor/CaSR 钙敏感受体1抗体
hz-8525R DNA Polymerase beta DNA聚合酶β抗体
hz-8526R STIM1 基质交感分子1抗体
hz-8527R VANGL1/LPP2 肿瘤抑制基因LPP2抗体
hz-8528R TPP1/CLN2 细胞生长抑制基因1蛋白抗体
hz-8529R D.Aspartic acid D型天冬氨酸抗体
hz-8530R SDHC 琥珀酸细胞色素亚基B560抗体
hz-8536R Nucleolin/C23 核仁蛋白C23抗体
hz-8537R Thymidylate synthase/TS 胸苷酸合成酶抗体
hz-8538R EP4R/Prostaglandin E Receptor EP4 前列腺素E受体蛋白4抗体
hz-8539R Luciferase 荧光素酶抗体
hz-8540R TSHZ3/ZNF537 锌指蛋白537抗体
hz-8541R CLECSF9/CLEC 4E C型凝集素4家族E抗体
hz-8542R MSH3 错配修复蛋白3抗体
hz-8543R PPY/Pancreatic hormone 胰腺激素抗体
hz-8544R GABR B3/GABA A Receptor beta 3 G氨基丁酸受体3抗体
hz-8546R KRIT1 脑海绵状血管畸形蛋白1抗体
hz-8547R HPV16 L2 人乳头瘤病毒16型L2抗体
hz-8548R OLIG1 少突胶质细胞转录因子1
hz-8549R SH2B1 SH2B蛋白抗体
hz-8550R Coronin 1a 肌动蛋白结合蛋白CORO1A抗体
hz-8551R Nitrotyrosine 硝基酪氨酸抗体
hz-8552R XDH/Xanthine Oxidase 黄嘌呤氧化酶抗体
hz-8553R phospho-CstF64(Ser498) 磷酸化细胞分裂相关蛋白CSTF64抗体
hz-8554R Hhzoglobin Beta 血红蛋白β抗体
hz-8555R Desmuslin 中间丝蛋白β-synhzin抗体
更多
企业名称
上海沪震生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001371133
成立日期
2014-05-08
注册资本
1000
经营范围
上海沪震生物科技有限公司
公司地址
上海市杨浦区密云路1018号复旦科技园808室
客服电话