英文名称 Anillin
中文名称 胞环蛋白肌动蛋白结合蛋白抗体
别 名 Actin binding protein scraps homolog Drosophila; Actin binding protein anillin; Anillin actin binding protein; ANLN; DKFZp779A055; Scra; Scraps; Scraps homolog.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 细胞周期蛋白 结合蛋白 细胞骨架
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 胞环蛋白肌动蛋白结合蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Anillin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
胞环蛋白肌动蛋白结合蛋白抗体产品介绍 background:
?Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis. Before the cell exits into G1, Anillin associates with E-cadherin and is ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C). APC/C recognizes the D-box domain at the N-terminal region of Anillin. Anillin is commonly overexpressed in tumors and may serve as a potential biomarker.Anillin is required for cytokinesis. It is essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.
Function:
Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.
胞环蛋白肌动蛋白结合蛋白抗体公司更多热销抗体产品如下:
hz-1319 F VIII Ag ELISA Kit 大鼠第八因子相关抗原
hz-1320 TIMP-2(Human tissue inhibitors of metalloproteinase 2) ELISA Kit 人基质金属蛋白酶抑制因子2
hz-1320 M2-PK ELISA Kit 大鼠丙酮酸激酶M2型同工酶
hz-1320 histon-H2b(Mouse histon-H2b) ELISA Kit 小鼠组蛋白H2b
hz-1321 AChRab ELISA Kit 大鼠乙酰胆碱受体抗体
hz-1321 OSM(Human Oncostatin-M) ELISA KIT 人抑瘤素M
hz-1321 VCAM-1/CD106(Mouse Vascuolar cell adhesion molecule 1) ELISA Kit 小鼠血管内皮细胞粘附分子1
hz-1322 GR(Mouse glucocorticoid receptor) ELISA Kit 小鼠糖皮质类固醇受体
hz-1322 GABA ELISA Kit 大鼠γ氨基丁酸
hz-1322 SP-D(Human Pulmonary surfatcant-associated protein D) ELISA Kit 人肺表面活性物质相关蛋白D
hz-1323 5-HT ELISA Kit 大鼠5羟色胺
hz-1323 SP-C(Human Pulmonary surfatcant-associated protein C) ELISA Kit 人肺表面活性物质相关蛋白C
hz-1323 LHRH(Mouse Luteinizing Hormone-Releasing Hormone) ELISA Kit 小鼠黄体生成素释放激素
hz-1324 SP-B(Human Pulmonary surfatcant-associated protein B) ELISA Kit 人肺表面活性物质相关蛋白B
hz-1324 SP-R ELISA Kit 大鼠P物质受体
hz-1324 NGB(Mouse Neuroglobin) ELISA Kit 小鼠脑红蛋白
hz-1325 8-iso-PG(Mouse 8-iso prostaglandin) ELISA Kit 小鼠8异前列腺素
hz-1325 SP-A(Human Surfactant Protein A) ELISA Kit 人表面活性蛋白A
hz-1325 SP ELISA Kit 大鼠P物质
hz-1326 AFU ELISA Kit 大鼠αL岩藻糖苷酶
hz-1326 MP-Ab(Human Mycoplasma pneumoniae antibody) ELISA Kit 人肺炎支原体抗体
hz-1326 IFI16/p16(Mouse interferon-inducible protein 16) ELISA Kit 小鼠γ干扰素诱导蛋白16/p16
hz-1327 TPO ELISA Kit 大鼠甲状腺过氧化物酶
hz-1327 SDF-1a/CXCL12(Mouse Stromal cell derived factor 1a) ELISA Kit 小鼠基质细胞衍生因子1a
hz-1327 Cpn-Ab(Human Chlamydia pneumoniae antibody) ELISA Kit 人肺炎衣原体抗体
hz-1328 VEGF(Mouse Vascular Endothelial cell Growth Factor) ELISA Kit 小鼠血管内皮细胞生长因子
hz-1328 LRP(Human Lung resistance-related protein) ELISA Kit 人肺耐药蛋白
hz-1328 PI ELISA Kit 大鼠胰岛素
更多
企业名称
上海沪震生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001371133
成立日期
2014-05-08
注册资本
1000
经营范围
上海沪震生物科技有限公司
公司地址
上海市杨浦区密云路1018号复旦科技园808室
客服电话