英文名称 Acylglycerol Kinase
中文名称 甘油酯激酶线粒体抗体
别 名 mitochondrial; Acylglycerol kinase; Acylglycerol kinase mitochondrial; agk; AGK_HUMAN; hAGK; HsMuLK; MuLK; Multi substrate lipid kinase; Multi-substrate lipid kinase; Multiple substrate lipid kinase.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 信号转导 激酶和磷酸酶 肿瘤细胞生物标志物 线粒体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 甘油酯激酶线粒体抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞浆 细胞膜 线粒体
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Acylglycerol Kinase
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
甘油酯激酶线粒体抗体产品介绍 background:
The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10.
Function:
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
甘油酯激酶线粒体抗体公司更多热销抗体产品如下:
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hz-2182PB Melamine/BSA 三聚氰胺偶联牛血清白蛋白
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六、标记蛋白质与多肽
编 号 名 称
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hzF-0326P Bovine IgG/FITC 荧光素标记牛IgG
hzF-0789P Insulin Protein/FITC 荧光素标记猪胰岛素蛋白
hzf-0327P Bovine IgM/FITC 荧光素标记牛IgM
hzF-0310P Chicken IgG/FITC 荧光素标记鸡IgG
hzf-0314P Chicken IgM/FITC 荧光素标记鸡IgM
hzf-0303P dog IgG/FITC 荧光素标记狗IgG
hzf-0373P dog IgM/FITC 荧光素标记狗IgM
hzF-0294P Goat IgG/FITC 荧光素FITC标记羊IgG(细胞流式同型对照)
hzf-0370P Goat IgM/FITC 荧光素标记羊IgM
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