醛糖还原酶相关蛋白质抗体

英文名称    AKR1B10    

中文名称    醛糖还原酶相关蛋白质抗体    

别    名    Aldose reductase like; Aldose reductase related protein; ARL 1; hARP; SI reductase; Small intestine reductase; AK1BA_HUMAN; AKR1B10; AKR1B11; AKR1B12; Aldo keto reductase family 1 member B10; aldo keto reductase family 1 member B11; Aldo-keto reductase family 1 member B10; aldose reductase like 1; aldose reductase like peptide; Aldose reductase-like; Aldose reductase-related protein; ALDRLn; ARL-1; ARL1; ARP; hARP; HIS; HSI; SI reductase; Small intestine reductase.    

说 明 书    0.2ml      

研究领域    肿瘤  信号转导  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 醛糖还原酶相关蛋白质抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    35kDa    

细胞定位    细胞浆 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human AKR1B10    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

醛糖还原酶相关蛋白质抗体产品介绍    background:

AKR1B10 is also known as aldose reductase-like-1 (ARL-1), small intestine reductase (SI reductase) or aldose reductase-related protein (ARP or hARP). AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon and adrenal gland. AKR1B10 is an efficient reductase for aliphatic and aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, and may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma and adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation and cellular response to carbonyl stress.

Function:
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.    

醛糖还原酶相关蛋白质抗体公司更多热销抗体产品如下：

hz-0770P SP-A (pulmonary surfactant-associated glycoprotein A)  肺表面活性蛋白A(抗原)

hz-0679P SYVN1(synovial apoptosis inhibitor 1)  滑膜细胞凋亡抑制物1（抗体）

hz-0685P SYK (Spleen tyrosine kinase)  非受体型酪氨酸激酶(抗原)

hz-0419P Tau protein  微管相关蛋白（抗原）

hz-0778P Thy-1/CD90  CD90(抗原)

hz-0632P Thioster-containing protein 1  硫酯包含蛋白-1(抗原)

hz-0640P TIGAR humen (TP53- induced glycolysis and apoptosis-regulator )  P53诱导糖酵解和凋亡调节因子蛋白（抗原）

hz-0418P TIMP-4(Tissue Inhibitor of Metalloproteinase-4)  金属蛋白酶组织抑制因子-4(抗原)

hz-0447P TPO(Thyroid Peroxidase)  甲状腺过氧化物酶(抗原)

hz-0460P TSHR (Thyroid stimulating hormone receptor)  促甲状腺素受体（抗原）

hz-0449P TSLP(Thymic stromal lymphopoietin isoform 1)  淋巴细胞生成素-1（抗原）

hz-0446P TTF-2(thyroid transcription factor 2;forkhead box E1)  甲状腺转录因子-2(抗原)

hz-0819P Tyrosinase  酪氨酸酶(多肽抗原)

hz-0603P OAT4L又称URAT1 (Urate Transporter 1)  尿酸盐重吸收转运子1 (抗原)

hz-0853P VAP1(vascular adhesion protein 1)  血管粘附蛋白1（多肽抗原）

hz-0756P Vimentin  波形蛋白（抗原）

hz-0479P VSIG4 (V-set and immunoglobulin domain-containing protein 4)  VSIG4 T淋巴细胞负调节蛋白之一（抗原）

hz-0429P WNK4(Ser/Thr-protein kinase WNK4; protein kinase with no lysine 4; protein kinase, lysine –dficient 4)  一种新的丝氨酸/苏氨酸激酶家族成员的基因WNK4（多肽抗原）

hz-0628P ZNF300 (zinc finger protein ZNF300)- middle  锌指蛋白300(抗原)

hz-0625P ZNF268 (zinc finger protein ZNF268)- N-terminal (1a)  锌指脂蛋白-1a(抗原)

hz-0626P ZNF268 (zinc finger protein ZNF268)- middle (1b)  锌指脂蛋白-1b(抗原）

hz-0627P ZNF268 (zinc finger protein ZNF268)- middle (1c)  人锌指脂蛋白-1c(抗原)