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雄激素受体相关蛋白24抗体

供货周期: 现货
品牌: CST
规格: g/mg
货号: hz-3751R
CAS号:
报价: ¥1
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产品介绍

英文名称    ARA24    

中文名称    雄激素受体相关蛋白24抗体    

别    名    Ran; Androgen receptor associated protein 24; ARA 24; ARA24; Gsp1; GTP binding nuclear protein RAN; GTPase Ran; LPS; RAN member RAS oncogene family; Ras like protein TC4; Ras related nuclear protein; RASL2 8; TC 4; TC4; RAN_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  生长因子和激素  转录调节因子  转运蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,雄激素受体相关蛋白24抗体 Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24kDa    

细胞定位    细胞核 细胞浆     

雄激素受体相关蛋白24抗体性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ARA24    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

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雄激素受体相关蛋白24抗体信息由上海沪震生物科技有限公司为您提供,如您想了解更多关于雄激素受体相关蛋白24抗体报价、型号、参数等信息,欢迎来电或留言咨询。除供应雄激素受体相关蛋白24抗体外,上海沪震生物科技有限公司还可为您提供SEK1/MKK4 (Ab-80) 抗体、p27Kip1 (Ab-10)抗体、Chk2 抗体等产品,公司有专业的客户服务团队,是您值得信赖的合作伙伴。
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雄激素受体相关蛋白24抗体

雄激素受体相关蛋白24抗体 Background: Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in Ran disrupt DNA synthesis. Because of its many functions, it is likely that Ran interacts with several other proteins. Ran regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. Ran could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of Ran-GTP around chromatin which, in turn, induces the local nucleation of microtubules. Ran is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). Ran coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease. Also known as: Ran; Androgen receptor associated protein 24; ARA 24; ARA24; Gsp1; GTP binding nuclear protein RAN; GTPase Ran; LPS; RAN member RAS oncogene family; Ras like protein TC4; Ras related nuclear protein; RASL2 8; TC 4; TC4; RAN_HUMAN.

24KB

2015/01/19

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