卷曲螺旋结构域蛋白68抗体(皮肤T淋巴细胞淋巴瘤相关抗原)
2015-02-27 10:39
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卷曲螺旋结构域蛋白68抗体(皮肤T淋巴细胞淋巴瘤相关抗原)
Background: CCDC68, also known as CTCL tumor antigen se57-1, is a 335 amino acid protein expressed in cutaneous T-cell lymphoma (CTCL), bone marrow, colon, small intestine, spleen, testis and trachea tissues. CTCL is a cancer of the immune system associated with mutation of the T cells. Malignant T cells form lesions on the surface of the skin. se57-1 contains 1 coiled coil domain and is encoded by the CCDC68 gene mapping to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also known as: CCD68_HUMAN; se57-1; CCDC 68; CCDC68; Coiled coil domain containing 68; Coiled coil domain containing protein 68; Coiled-coil domain-containing protein 68; CTCL associated antigen se57 1; CTCL tumor antigen se57 1; CTCL-associated antigen se57-1; Cutaneous T cell lymphoma associated antigen; Cutaneous T cell lymphoma associated antigen se57 1; Cutaneous T-cell lymphoma-associated antigen se57-1; FLJ25368; SE57 1.卷曲螺旋结构域蛋白68抗体(皮肤T淋巴细胞淋巴瘤相关抗原)
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