唾液酸结合性免疫球蛋白样凝集素5抗体

唾液酸结合性免疫球蛋白样凝集素5抗体 Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation. Also known as: SIGLEC5; CD170 antigen; CD33 antigen-like 2; CD33L2; mSiglec-F;OB-binding protein 2; OB-BP2; OBBP2; Obesity-binding protein 2; Sialic acid binding Ig-like lectin 5; Sialic acid binding immunoglobulin-like lectin 5; Sialic acid-binding Ig-like lectin F; SIGLEC-5; Siglec-F variant; Siglecf; SIGL5_HUMAN.唾液酸结合性免疫球蛋白样凝集素5抗体