骨碱性磷酸酶抗体
2015-01-28 10:55
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骨碱性磷酸酶抗体
Background: Defects in ALPL are a cause of hypophosphatasia (HOPS) . HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and adult type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia. Also known as: tissue-nonspecific isozyme; AKP2; Alkaline phosphatase; Alkaline phosphatase liver/bone/kidney isozyme; Alpl; AP-TNAP; HOPS; Liver/bone/kidney isozyme; PHOA; PPBT_HUMAN; Tissue non specific alkaline phosphatase; Tissue nonspecific ALP; TNAP; TNSALP.骨碱性磷酸酶抗体
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