磷酸化系统性红斑狼疮先关蛋白TREX1抗体
2015-01-26 08:57
浏览:44次
分享:
资料摘要:
磷酸化系统性红斑狼疮先关蛋白TREX1抗体
Background: DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints. Checkpoint proteins include Rad17, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, Chk2, Rad1, Rad9 and Hus1, which are involved in regulating cell cycle arrest at the G2 checkpoint. In response to DNA damage, ATM and ATR kinases are important for cell cycle checkpoint response signalling. ATR-interacting protein (ATRIP), also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage. It is also important for ATR expression, which regulates DNA replication and damage checkpoint responses. ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR. After dimerization they bind the RPA complex and are recruited to single stranded DNA. ATRIP is a nuclear protein that may also play a role in protein stabilization. Also known as: ATRIP (phospho S68 + S72); Phospho-ATRIP (Ser68 + Ser72); P-ATRIP (phospho-Ser68/Ser72); AGS 1; AGS1; AGS-1; Aicardi Goutieres syndrome 1; ATIP; ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR interacting protein; ATR-interacting protein; Atrip; ATRIP_HUMAN; Deoxyribonuclease III dnaQ/mutD (E. coli) like; DKFZp434J0310; DKFZp762J2115; DNase III; DRN 3; DRN3; FLJ12343; MGC20625; MGC26740; Three prime repair exonuclease 1; TREX 1; TREX1; TREX1 protein; MGC21482; 3' repair exonuclease 1; 3'-5' exonuclease TREX1.磷酸化系统性红斑狼疮先关蛋白TREX1抗体
下载本篇资料:
磷酸化系统性红斑狼疮先关蛋白1抗体.doc
23KB
推荐资料
大鼠胰岛素(INS)酶联免疫分析试剂盒用于测定大鼠血清,血浆及相关液体样本中胰岛素(INS)含量。本试剂盒仅供研究使用。
大鼠血管内皮生长因子 (VEGF)酶联免疫分析试剂盒用于测定大鼠血清,血浆及相关液体样本中血管内皮生长因子 (VEGF)含量。
大鼠胸肾表达趋化因子(BRAK/CXCL14)酶联免疫分析试剂盒用于测定大鼠血清、血浆及相关液体样本中胸肾表达趋化因子(BRAK/CXCL14)含量。
大鼠纤维蛋白原(FG)酶联免疫分析试剂盒用于测定大鼠血清血浆及相关液体样本中纤维蛋白原(FG)含量。