去整合素样金属蛋白酶19抗体
2015-01-21 09:20
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去整合素样金属蛋白酶19抗体
Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]. Also known as: A disintegrin and metalloproteinase domain 19 (meltrin beta); A disintegrin and metalloproteinase domain 19; ADAM 19; ADAM metallopeptidase domain 19; Disintegrin and metalloproteinase domain containing protein 19; FKSG 34; FKSG34; MADDAM; Meltrin beta; ADA19_HUMAN; Metalloprotease and disintegrin dentritic antigen marker; MLTN B; MLTNB.
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