芳香烃受体核转录蛋白2抗体
2015-01-21 09:14
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芳香烃受体核转录蛋白2抗体
Background: ARNT2 is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. It acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, ARNT2 protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. Also known as: ARNT protein 2; Aryl hydrocarbon receptor nuclear translocator 2.ARNT2_HUMAN
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