HIC-10 LC 色谱柱 088482

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MAbPac™ HIC-10 LC 色谱柱

Thermo Scientific™ MAbPac™ HIC-10 LC 色谱柱是一款高分离度硅胶柱，设计通过疏水相互作用来分离单克隆抗体 (MAb) 和相关生物制剂。 MabPac HIC-10 色谱柱具备独特的化学成分，可以提供高分离度、优异的生物相容性和选择性，不同于市场上其他 HIC 色谱柱。

专为 MAb 最佳选择性而设计的独特化学成分

MAbPac HIC-10 色谱柱中填充有高纯度、球型、粗孔径 (1,000) 的 5μm 硅胶颗粒，这些硅胶颗粒采用具有专利技术的烷基酰胺基团进行功能化。 其 先进的表面键合技术使该色谱柱具备优异的化学稳定性、高柱效以及对 MAb 独特的最佳选择性，与其他 HIC 键合相与众不同。

• 优异的生物相容性和极低残留

• 高分离度和高柱效

• 同时兼容有机溶剂和水性流动相

• 耐用的色谱柱稳定性

MAbPac HIC Family

The MAbPac HIC column family is designed for separations of monoclonal antibodies (mAbs) and related biologics by hydrophobic interaction chromatography (HIC). These columns are designed to address the separation challenges as the result of heterogeneity, complexity and diversity of mAbs and related biologics.

Applications
The MAbPac HIC-10 is the column of choice for intact mAbs/proteins and mAb aggregates while the MAbPac HIC-20 is suited to resolve mAb fragments, oxidized mAbs and bispecific mAbs. When it comes to ADCs, MAbPac HIC-Butyl is ideal for cystein-conjugated ADC while MAbPac HIC-10 and MAbPac HIC-20 have proven useful for several cysteine proprietary
ADC molecules, as shown below.

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