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ProPac™ WCX-10 LC 色谱柱
使用 Thermo Scientific™ ProPac™ WCX-10 LC 色谱柱为蛋白及其变体的分离提供超高分离度。 基于由 10 μm 无孔聚合微球组成的固定相，ProPac 色谱柱可分辨仅有单一电荷残留差异的蛋白异形体。 键合的亲水层避免了多余的次级相互作用。 阳离子交换表面提供基于 pH 的选择性控制，为高效分离和稳健性能提供快速传质功能。
更大灵活性的多种规格
ProPac WCX-10 色谱柱是一种带羧基官能团的弱阴离子交换柱
针对分析工作，色谱柱最小内径为 2 mm，而针对半制备工作，内径可达 22 mm
蛋白分析的卓越性能
非常适合单克隆抗体和其他蛋白的表征和质量控制评估
可用于表征结构相近的蛋白变体，包括脱氨基和 MAb 赖氨酸截断变体
无与伦比的高分离度分离
无与伦比的柱到柱和批到批的可重现性避免了在稳定性和 QA/QC 测试中对色谱柱变异性的担忧。
ProPac HPLC Columns
ProPac WCX-10 and SCX-10
Weak and strong cation exchange columns with exceptionally high resolution and efficiency for separations of protein variants
* Characterization and quality control assessment of monoclonal antibodies and other proteins
* Exceptionally high-resolution and high-efficiency separations
* Useful for characterization of related protein variants including deamidation and mAb lysine truncation variants
* ProPac WCX-10 contains carboxylate functional groups and ProPac SCX-10 contains sulfonate functional groups
ProPac WCX-10 and SCX-10 columns are non-porous particles that can resolve isoforms that differ by a single charged residue. A hydrophilic layer prevents unwanted secondary interactions, and a grafted cation exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
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订购信息：
| ProPac WCX-10 | ||||||
| Particle Size (μm) | Format | Length(mm) | 2.0mm ID | 4.0mm ID | 9.0mm ID | 22.0mm ID |
10
| Guard Column | 50 | 063480 | 054994 | – | – |
HPLC Column | 50 | – | 074600 | – | – | |
| 100 | – | 088778 | – | – | ||
| 150 | – | 088778 | – | – | ||
| 250 | 063472 | 054993 | 063474 | 088766 | ||
| ProPac SCX-10 | ||||||
| Particle Size (μm) | Format | Length (mm) | 2.0mm ID | 4.0mm ID | 9.0mm ID | 22.0mm ID |
10 | Guard Column | 50 | 063462 | 079930 | – | – |
| HPLC Column | 250 | 063456 | 054995 | 063700 | 088769 | |
| ProPac Kits | |||
Part Number | Phase Description | Set Contents | Column Dimensions |
088776 | ProPac WAX-10 Lot Select Column Set | 3 columns from 1 lot of resin | 250 x 4.0mm |
088777 | ProPac WAX-10 Lot Select Column Set | 3 lots of resin, 1 column from each lot | 250 x 4.0mm |
088774 | ProPac SAX-10 Lot Select Column Set | 3 columns from 1 lot of resin | 250 x 4.0mm |
088775 | ProPac SAX-10 Lot Select Column Set | 3 lots of resin, 1 column from each lot | 250 x 4.0mm |
088767 | ProPac WCX-10 Lot Select Column Set | 3 columns from 1 lot of resin | 250 x 4.0mm |
088768 | ProPac WCX-10 Lot Select Column Set | 3 lots of resin, 1 column from each lot | 250 x 4.0mm |
088772 | ProPac SCX-10 Lot Select Column Set | 3 columns from 1 lot of resin | 250 x 4.0mm |
088773 | ProPac SCX-10 Lot Select Column Set | 3 lots of resin, 1 column from each lot | 250 x 4.0mm |
北京谱朋科技有限公司
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