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瑞士万通Multi Autolab/M204多通道电化学工作站型号： Multi Autolab/M204 -
德国FRITSCH P7 小型行星式球磨机/仪加强型型号： PULVERISETTE 7 premium line -
激光干涉仪型号： XL80 -
Hitachi日立CT15RE台式离心机型号： CT15RE -
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日立Primaide PLUS高效液相色谱仪型号： Primaide PLUS
获取电话Twisted Gastrulation Protein (TSG) is a secreted BMP-binding protein that is structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP-4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP-4/Chordin complex. Recombinant Human TSG is a 198 amino acid, 22.2 kDa protein containing the BMP/TGF-β binding portion of the full length TSG protein.
Source: E.coli
Synonyms: Twisted Gastrulation Protein
AA Sequence: CNKALCASDV SKCLIQELCQ CRPGEGNCSC CKECMLCLGA LWDECCDCVG MCNPRNYSDT PPTSKSTVEE LHEPIPSLFR ALTEGDTQLN WNIVSFPVAE ELSHHENLVS FLETVNQPHH QNVSVPSNNV HAPYSSDKEH MCTVVYFDDC MSIHQCKISC ESMGASKYRW FHNACCECIG PECIDYGSKT VKCMNCMF
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to neutralize BMP-6-induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is ≤ 2.0 μg/ml of TSG.
Calculated Molecular Weight: 22.2 kDa
Accession Number: Q9GZX9
Gene ID: 57045
Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
crossreactivity:
