Animal-Free Recombinant Human BMP-4 (E.coli derived)
价格： 面议
品牌：派普泰克
供货周期： 两周
货号：AF-120-05ET-100ug
规格：100ug
获取电话Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa.
Manufactured using all Animal-Free reagents.
Source: E.coli
Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4
AA Sequence (monomer): KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Calculated Molecular Weight: 23.9 kDa
Accession Number: P12644
Gene ID: 652
Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)
Note:
1mg will be provided as 2x500μg.
crossreactivity:
