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FGF-16 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant Human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues.
Source: E.coli
Synonyms: Fibroblast Growth Factor-16, FGFG
AA Sequence: AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR
Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.
Calculated Molecular Weight: 23.6 kDa
Accession Number: O43320
Gene ID: 8823
Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
Note:
250μg is the largest vial size for this product.
Larger sizes supplied as multiple 250μg vials.
Cross Reactivity Cited in References:
Human, Mouse, Rat
