获取电话
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues.
Source: E.coli
Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
AA Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Recombinant Human FGF-acidic Biological Activity Graph
Calculated Molecular Weight: 16.8 kDa
Accession Number: P05230
Gene ID: 2246
Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
crossreactivity:
Cow, Hagfish, Hamster, Human, Leech, Mouse, Pig, Rat, Shark, Squid
