获取电话别称
AXIN
宿主
Rabbit
适应种属
Human
亚型
IgG
验证应用
ELISA, WB
产品信息
产品名称
anti- AXIN1 antibody
货号
QSab00752
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
宿主
Rabbit
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
背景介绍
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.
免疫原信息
免疫原
axin 1
别称
AXIN
分子量
100-110kd
应用
验证应用
ELISA, WB
anti- AXIN1 antibody多少钱?
钦胜生物抗体/抗原的应用资料有吗？
钦胜生物抗体/抗原货号QSab00752报价含票含运吗？
钦胜生物货号QSab00752货期是多久？
QCBIOanti- AXIN1 antibody可以申请试用吗？
QCBIO钦胜生物抗体/抗原售后政策是什么？
anti- AXIN1 antibody有现货吗？