获取电话CHIT1 抗原（重组蛋白）
中文名称： CHIT1 抗原（重组蛋白）
英文名称： CHIT1 Antigen (Recombinant Protein)
别 名： chitinase 1; CHI3; CHIT; CHITD
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
Fusion protein corresponding to a region derived from 267-466 amino acids of human CHIT1
技术规格
Full name: | chitinase 1 |
Synonyms: | CHI3; CHIT; CHITD |
Swissprot: | Q13231 |
Gene Accession: | BC103695 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. |
