获取电话小鼠抗ZFAND5单克隆抗体
中文名称: 小鼠抗ZFAND5单克隆抗体
英文名称: Anti-ZFAND5 mouse monoclonal antibody
别 名: ZA20D2; ZFAND5A; ZNF216
储 存: 冷冻（-20℃） 避光
抗 原: ZFAND5
宿 主: Mouse
反应种属: Human
相关类别: 一抗
标 记 物: Unconjugate
克隆类型: mouse monoclonal
技术规格: 小鼠抗ZFAND5单克隆抗体
Background: | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
Applications: | WB |
Name of antibody: | ZFAND5 |
Immunogen: | Fusion protein of human ZFAND5 |
Full name: | zinc finger, AN1-type domain 5 (ZFAND5), transcript variant c |
Synonyms: | ZA20D2; ZFAND5A; ZNF216 |
SwissProt: | O76080 |
WB Predicted band size: | 23 kDa |
WB Positive control: | A549 cell lysate |
WB Recommended dilution: | 500-2000 |
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