仪器信息网 试剂标物 生化试剂 蛋白质/多肽 Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His), 小鼠蛋白S100 Calcium Binding Protein B/S100B (C-6His)
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产品描述:

产品名称:Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His)

描述: Recombinant Mouse S100 Calcium Binding Protein B is produced by our E.coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the C-terminus.

氨基酸序列: MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDEDG DGECDFQEFMAFVAMVTTACHEFFEHELEHHHHHH

背景说明: S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.

别名: Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100b, S100 beta, S100 calcium binding protein B

Accession: P50114

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04491   Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His)   10ug   798.00   立即咨询
  abs04491   Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His)   50ug   2100.00   立即咨询
  abs04491   Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His)   500ug   12936.00   立即咨询
  abs04491   Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His)   1mg   17600.00   立即咨询

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生化试剂 Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His), 小鼠蛋白S100 Calcium Binding Protein B/S100B (C-6His)由爱必信(上海)生物科技有限公司为您提供,如想了解更多关于蛋白质/多肽 Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His), 小鼠蛋白S100 Calcium Binding Protein B/S100B (C-6His)的报价、规格、厂家等信息,欢迎来电或留言咨询。除供应Recombinant Mouse S100 Calcium Binding Protein B/S100B (C-6His), 小鼠蛋白S100 Calcium Binding Protein B/S100B (C-6His)外,爱必信(上海)生物科技有限公司还可为您提供:

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