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抑制剂描述: 产品名称:PCI 29732 产品别名:见爱必信官网 英文别名:PCI 29732 靶点:BTK CAS:330786-25-9 纯度: 外观:见爱必信官网 保存方法: 描述:PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.IC50 value: 8.2 nM [1]Target: Btk kinasePCI 29732(compound 1) has a 8.2 nM potency against Btk in a FRET based biochemical enzymology assay. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase, probably due to the difference at the “gatekeeper” residue [1].In human CD20+ B cells stimulated at the BCR, PCI-29732 blocked the transcriptional up-regulation of a panel of B-cell activation genes that occurs within 6 h of stimulation. Pulse exposure to the reversible inhibitor PCI-29732 did not result in BCR inhibition [2]. 溶解性:DMSO: ≥ 53 mg/mL 体外研究: 体内研究:
产品信息订购:
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PCI 29732多少钱?
爱必信生物分子的应用资料有吗?
爱必信生物分子货号abs818924报价含票含运吗?
爱必信货号abs818924货期是多久?
爱必信PCI 29732可以申请试用吗?
爱必信爱必信生物分子售后政策是什么?
PCI 29732有现货吗?