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仪器信息网试剂标物生化试剂生物分子 Diethyl-pythiDC

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Diethyl-pythiDC

价格：￥ 2772

品牌：爱必信

供货周期： 7天

货号：abs821263

型号：98%

CAS：1821370-70-0

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抑制剂描述：

产品名称：Diethyl-pythiDC

产品别名：见爱必信官网

英文别名：Diethyl-pythiDC

靶点：Others

CAS：1821370-70-0

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).

溶解性：

体外研究：

Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 μM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin.

体内研究：Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 μM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs821263	Diethyl-pythiDC	5mg	2772.00	立即咨询
abs821263	Diethyl-pythiDC	25mg	9828.00	立即咨询

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