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DL-Penicillamine

DL-Penicillamine

价格: 363

品牌:爱必信

供货周期: 一周

货号:abs816991

规格:>98%

CAS:52-66-4

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抑制剂描述:

产品名称:DL-Penicillamine

产品别名:见爱必信官网

英文别名:DL-Penicillamine

靶点:Others

CAS:52-66-4

纯度:>98%

外观:见爱必信官网

保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

描述:

DL-Penicillamine is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL-Penicillamine also reduces excess cystine excretion in cystinuria. This is done, at least in part, by disulfide interchange between DL-penicillamine and cystine, resulting in the formation of penicillamine-cysteine disulfide, a substance that is much more soluble than cysteine and is excreted readily. DL-Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. The mechanism of action of DL-penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, DL-penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, DL-penicillamine in vitro depresses T-cell activity but not B-cell activity.

溶解性:Free soluble in water.

体外研究:

体内研究:

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs816991   DL-Penicillamine   5mg   363.00   立即咨询
  abs816991   DL-Penicillamine   10mg   389.00   立即咨询
  abs816991   DL-Penicillamine   25mg   767.00   立即咨询
  abs816991   DL-Penicillamine   50mg   1229.00   立即咨询

产品更多信息请进入爱必信网站咨询




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