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SUN 1334H

SUN 1334H

价格: 1260

品牌:爱必信

供货周期: 一周

货号:abs822424

CAS:607736-84-5

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抑制剂描述:

产品名称:SUN 1334H

产品别名:见爱必信官网

英文别名:SUN 1334H

靶点:H1 receptor

CAS:607736-84-5

纯度:

外观:见爱必信官网

保存方法:store at -20℃ for one year(Powder)

描述:SUN 1334H is a potent, orally active, highly selective H1 receptor antagonist, with Ki of 9.7 nM.

溶解性:DMSO*

体外研究:

SUN-1334H causes potent inhibition of histamine induced contractions of isolated guinea-pig ileum with an IC50 (half the maximal inhibitory concentration) of 0.198 μM. In CHO-K1/hERG cells, SUN-1334H does not modulate hERG K+-currents at concentrations as high as 100 μM. SUN-1334H, cetirizine and hydroxyzine cause comparable inhibition of NLF leukocytes, IL-4 and total protein concentrations.

体内研究:SUN-1334H causes potent inhibition of histamine induced contractions of isolated guinea-pig ileum with an IC50 (half the maximal inhibitory concentration) of 0.198 μM. In CHO-K1/hERG cells, SUN-1334H does not modulate hERG K+-currents at concentrations as high as 100 μM. SUN-1334H, cetirizine and hydroxyzine cause comparable inhibition of NLF leukocytes, IL-4 and total protein concentrations.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs822424   SUN 1334H   1mg   1260.00   立即咨询
  abs822424   SUN 1334H   5mg   2520.00   立即咨询

产品更多信息请进入爱必信网站咨询




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