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一键询价梅里埃 10400奈瑟氏球菌嗜血菌鉴定盒API NH
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梅里埃 API氧化酶试剂
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CCFSTTG1 人脑星形细胞瘤 QCH828
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MM28 人眼葡萄膜黑色瘤細胞 QCH829
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5500¥
HCC202 人乳腺原发性导管癌 QCH830
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3000¥
HCC2157 人乳腺导管癌细胞(三阴性)QCH831
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5000¥
hCMEC/D3-RFP红色荧光蛋白标记的人脑微血管内皮细胞 QCH346R
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KHYG-1 人NK细胞淋巴瘤细胞 QCH833
一周
3500¥
NCI-h1869 人非小细胞肺癌鳞癌细胞 QCH834
一周
3500¥
NCI-H1417 人小细胞肺癌细胞 QCH835
钦诚生物 | 一周
3500¥
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抑制剂描述: 产品名称:Kainic acid 产品别名:见爱必信官网 英文别名:Kainic acid 靶点:mGluR CAS:487-79-6 纯度:≥98% 外观:见爱必信官网 保存方法:Store at -20℃ 描述: Kainic acid is a marine natural product bearing structural analogy to the neurotransmitter glutamate that produces neuroexcitatory agonist effects at the kainate ionotropic receptors. The kainate receptors are non-NMDA glutamate-recognizing ionotropic receptors, and agonism by Kainic acid or glutamate produces excitation and contribution to excitatory postsynaptic currents. Agonism of the kainate receptors by sufficient concentrations of Kainic acid produces excitotoxicity, and Kainic acid is widely employed as a tool for inducing excitotoxic seizures in neurotransmission studies. Kainic acid is employed alongside the agonists NMDA and AMPA to identify the specific subtype of glutamate-recognizing receptors of interest. A caged version of this compound is available. 溶解性:Soluble in water (25 mg/ml), dilute hydrochloric acid, and solutions of alkali hydroxide. Insoluble in ethanol. 体外研究: Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus. 体内研究:
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