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Alniditan

Alniditan

价格: 16128

品牌:爱必信

供货周期: 一周

货号:abs820897

CAS:152317-89-0

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抑制剂描述:

产品名称:Alniditan

产品别名:见爱必信官网

英文别名:Alniditan

靶点:5-HT Receptor

CAS:152317-89-0

纯度:

外观:见爱必信官网

保存方法:store at -20℃ for one year(Powder)

描述:Alniditan is a potent 5-HT1B/1D receptors agonist, with IC50 of 1.7 and 1.3 nM in HEK?293 cells, and pKi value of 8.96 and 9.40 for 5-HT1B/1D receptors, respectively.

溶解性:DMSO*

体外研究:

In vitro, alniditan exhibits little vasoconstrictive effects on the rat basilar artery, although at a very high concentration 1 mM, alniditan causes intensive constriction, most likely through a mechanism independent from 5-HT receptor activation. Alniditan is 10 times more potent than sumatriptan at the h5-HT1B receptor, and twice as potent at the h5-HT1D receptor.

体内研究:In vitro, alniditan exhibits little vasoconstrictive effects on the rat basilar artery, although at a very high concentration 1 mM, alniditan causes intensive constriction, most likely through a mechanism independent from 5-HT receptor activation. Alniditan is 10 times more potent than sumatriptan at the h5-HT1B receptor, and twice as potent at the h5-HT1D receptor.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs820897   Alniditan   1mg   16128.00   立即咨询
  abs820897   Alniditan   5mg   32256.00   立即咨询

产品更多信息请进入爱必信网站咨询




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