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Pizotifen malate

Pizotifen malate

价格: 482

品牌:爱必信

供货周期: 一周

货号:abs819165

规格:>98%

CAS:5189-11-7

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抑制剂描述:

产品名称:Pizotifen malate

产品别名:见爱必信官网

英文别名:Pizotifen malate

靶点:5-HT Receptor

CAS:5189-11-7

纯度:>98%

外观:见爱必信官网

保存方法:Store at -20°C

描述:

Pizotifen malate, a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.

溶解性:DMSO : 20 mg/mL (46.6 mM)

体外研究:

Pizotifen is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. Pizotifen is an antidepresent 5-HT2A receptor antagonist and has the capacity to inhibit serotonin-enhanced ADP-induced platelet aggregation.

体内研究:The weights of the fetuses are significantly reduced by all administered doses of Pipethiadene and Pizotifen malate; the weights of the placentas are significantly reduced after 0.6 and 1.2 mg/kg Pipethiadene and only after the middle dose of Pizotifen malate. The means of the implantations, live, dead fetuses, resorptions and the occurrence of external, skeletal and visceral anomalies do not differ from the control group. The number of chromosome aberrations in the bone marrow cells of treated mice does not differ significantly from the negative control group. The micronucleus test reveals no elevation in the frequency of micronuclei as compared to the control group. After the two higher doses of both Pipethiadene and Pizotifen maleate, the mitotic indices are lower than in the control group.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs819165   Pizotifen malate   100mg   482.00   立即咨询
  abs819165   Pizotifen malate   200mg   794.00   立即咨询

产品更多信息请进入爱必信网站咨询




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