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一键询价MKN1 人胃癌细胞 QCH812
一周
3500¥
Phoenix-AMPHO 人肾上皮细胞 QCH813
一周
5500¥
DBTRG-05MG 人脑胶质细胞瘤细胞 QCH814
一周
3500¥
SNU638 人胃癌细胞 QCH815
一周
3500¥
NCI-H2073 人非小细胞肺癌细胞 QCH816
一周
5500¥
HAL01 人急性淋巴细胞白血病细胞 QCH817
一周
2500¥
TMD8 人弥漫性大B细胞淋巴瘤 QCH818
一周
7500¥
SNU484 人胃癌细胞 QCH819
一周
3500¥
JHH2 人肝癌细胞 QCH820
一周
4500¥
LK2 人肺腺癌细胞 QCH821
钦诚生物 | 一周
3500¥
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抑制剂描述: 产品名称:STA-21 产品别名:见爱必信官网 英文别名:STA-21 靶点:STAT CAS:111540-00-2 纯度:99.66 % 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述:STA-21 is a selective <b>STAT3</b> inhibitor. 溶解性:: 体外研究: In cells, STA-21 inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity. STA-21 remarkably inhibits the growth and the survival of the breast carcinoma cells MDA-MB-231, MDA-MB-435s, and MDA-MB-468 that express persistently activated Stat3. In RH30 and RD2 cells, STA-21 also inhibits cell viability and growth and induced apoptosis through caspases 3, 8 and 9 pathways. 体内研究:In IL-1Ra–KO mice, STA-21 (0.5 mg/kg, i.p.) reduces the arthritis score and the incidence of arthritis by decreasing the proportion of Th17 cells and increasing the proportion of Treg cells expressing FoxP3.
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