找不到产品?留下需求帮您找
一键询价梅里埃 10400奈瑟氏球菌嗜血菌鉴定盒API NH
两周
面议
梅里埃 API氧化酶试剂
两周
面议
CCFSTTG1 人脑星形细胞瘤 QCH828
一周
3500¥
MM28 人眼葡萄膜黑色瘤細胞 QCH829
一周
5500¥
HCC202 人乳腺原发性导管癌 QCH830
一周
3000¥
HCC2157 人乳腺导管癌细胞(三阴性)QCH831
一周
5000¥
hCMEC/D3-RFP红色荧光蛋白标记的人脑微血管内皮细胞 QCH346R
一周
3500¥
KHYG-1 人NK细胞淋巴瘤细胞 QCH833
一周
3500¥
NCI-h1869 人非小细胞肺癌鳞癌细胞 QCH834
一周
3500¥
NCI-H1417 人小细胞肺癌细胞 QCH835
钦诚生物 | 一周
3500¥
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:Tiplaxtinin(PAI-039) 产品别名:见爱必信官网 英文别名:Tiplaxtinin(PAI-039) 靶点:PAI-1 CAS:393105-53-8 纯度:>98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. 描述:Inhibitor of plasminogen activator inhibitor-1 (PAI-1) 溶解性:DMSO 72 mg/mL (163.86 mM) 体外研究: In a panel of human bladder cell lines, PAI-1 results in the reduction of cellular proliferation, cell adhesion, and colony formation, and the induction of apoptosis and anoikis. 体内研究:In a rat carotid thrombosis model, Tiplaxtinin (1 mg/kg, p.o.) increases time to occlusion and prevents the carotid blood flow reduction. In C57BL/6J mice, (1 mg/g chow) attenuates Ang II-induced aortic remodeling. In untreated type 1 diabetic mice, Tiplaxtinin (p.o.) restores skeletal muscle regeneration. In athymic mice bearing human cancer cell line T24 and HeLa xenografts, Tiplaxtinin (1 mg/kg, p.o.) reduces tumor xenograft growth, associated with a reduction in tumor angiogenesis, a reduction in cellular proliferation, and an increase in apoptosis.
产品信息订购:
|