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Epigallocatechin Gallate

Epigallocatechin Gallate

价格: 294

品牌:爱必信

供货周期: 一周

货号:abs812943

规格:≥98%

CAS:989-51-5

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抑制剂描述:

产品名称:Epigallocatechin Gallate

产品别名:见爱必信官网

英文别名:Epigallocatechin Gallate

靶点:Telomerase

CAS:989-51-5

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20°C

描述:

Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors.

溶解性:Ethanol :45.8 mg/mL (100 mM)
DMSO :4.6 mg/mL (10 mM)
Water :4.6 mg/mL (10 mM)

体外研究:

(-)-Epigallocatechin Gallate (EGCG) inhibits activation EGFR, HER2 and HER3 in the SW837 human colon cancer cell line. (-)-Epigallocatechin Gallate (10 μM) also inhibits cell growth, suppresses activation of EGFR, HER2, and HER3, and causes decrease in the levels of COX-2 and Bcl-xL proteins, and apoptosis after treatment for 96 h. (-)-Epigallocatechin Gallate (0-35 μg/mL) inhibits the proliferation of colorectal cancer cells. (-)-Epigallocatechin Gallate (35 μg/mL) induces apoptosis of colorectal cancer cells. (-)-Epigallocatechin Gallate (EGCG; 50, 75 and 100 μM) dose-dependently inhibits the growth of HepG2 cells, and induces apoptosis in HepG2 cells.

体内研究:(-)-Epigallocatechin Gallate (5, 10, and 20 mg/kg, p.o.) inhibits the growth of orthotopic colorectal cancer cells in mice.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs812943   Epigallocatechin Gallate   25mg   294.00   立即咨询
  abs812943   Epigallocatechin Gallate   50mg   426.00   立即咨询
  abs812943   Epigallocatechin Gallate   200mg   671.00   立即咨询

产品更多信息请进入爱必信网站咨询




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