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仪器信息网试剂标物生化试剂生物分子 Endothelin-2, human

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爱必信(上海)生物科技有限公司

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Endothelin-2, human

价格：￥ 3931

品牌：爱必信

供货周期： 7天

货号：abs820410

CAS：123562-20-9

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产品名称：Endothelin-2, human

产品别名：见爱必信官网

英文别名：Endothelin-2, human

靶点：ERR

CAS：123562-20-9

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外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Endothelin-2, human is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

溶解性：

体外研究：

At nanomolar concentrations, Endothelin-2 exhibits a strong and long-lasting vasoconstrictor activity characteristic of endothelin (EC50=0.52 nM). Endothelin-2 is a chemoattractant for macrophages and THP-1 monocytic cells, but not for freshly isolated monocytes. The chemotactic response to Endothelin-2 shows a typical bell-shaped response curve. Experiments with endothelin receptor antagonists shows that migration to Endothelin-2 is mediated via the ET-RB receptor. Endothelin-2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.

体内研究：At nanomolar concentrations, Endothelin-2 exhibits a strong and long-lasting vasoconstrictor activity characteristic of endothelin (EC50=0.52 nM). Endothelin-2 is a chemoattractant for macrophages and THP-1 monocytic cells, but not for freshly isolated monocytes. The chemotactic response to Endothelin-2 shows a typical bell-shaped response curve. Experiments with endothelin receptor antagonists shows that migration to Endothelin-2 is mediated via the ET-RB receptor. Endothelin-2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs820410	Endothelin-2, human	500ug	3931.00	立即咨询

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