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肿瘤易感候选基因3抗体

肿瘤易感候选基因3抗体

价格: 1580

品牌:LMAI Bio

供货周期: 现货

货号:LM4097R

型号:50ul/100ul/200ul

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肿瘤易感候选基因3抗体

 

英文名称    CASC3    

中文名称    肿瘤易感候选基因3抗体    

别    名    Barentsz protein; Btz; Cancer susceptibility candidate gene 3 protein; Metastatic lymph node protein 51; MLN 51 protein; MLN51; Protein barentsz; Protein CASC3; Protein MLN 51; MLN51; CASC3_HUMAN.      

研究领域    肿瘤  细胞生物  免疫学  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Cow, Horse,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    76kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CASC3/MLN51:501-600/703     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exon–exon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.    





生化试剂 肿瘤易感候选基因3抗体由上海联迈生物工程有限公司为您提供,如想了解更多关于抗体/抗原 肿瘤易感候选基因3抗体的报价、规格、厂家等信息,欢迎来电或留言咨询。除供应肿瘤易感候选基因3抗体外,上海联迈生物工程有限公司还可为您提供: 冻干Fast DNA TaqMan PCR Reagent、 阿魏酸 CAS:1135-24-6、 Methyl 6-acetoxyangolensate CAS:16566-88-4

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