获取电话Quantity size:
0.2ml
Concentration:
1mg/ml 早期生长应答蛋白1靶向蛋白1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
TOE1 is a 510 amino acid long protein that belongs to the CAF1 family. It is a downstream target of EGR-1 and plays an important role mediating the inhibitory growth effect of EGR-1. EGR-1 directly binds the TOE1 promoter region and activates its expression. TOE1 induces the expression of TGF∫ and p21 and plays a role in cell cycle regulation and the inhibition 早期生长应答蛋白1靶向蛋白1抗体of cell growth. The activity and nucleolar localization of TOE1 correlates with a G2 cell cycle phase delay which is likely due to an increased expression of p21. In addition, TOE1 may function via an interaction with p53 and possible modification to its activity. TOE1 is expressed at various levels in all adult tissues and specifically localizes to the 早期生长应答蛋白1靶向蛋白1抗体nuclear speckles.
Also known as:
Target of EGR1 protein 1; target of EGR1, member 1; Toe1; TOE1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, 早期生长应答蛋白1靶向蛋白1抗体affinity purified by Protein A.
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Reacts with: Human, .
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早期生长应答蛋白1靶向蛋白1抗体Immunogen: KLH conjugated synthetic peptide derived from human TOE1.
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Predicted Molecular Weight: 57kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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