阅读障碍相关蛋白Shootin抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 阅读障碍相关蛋白Shootin抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Shootin1 is a 631 amino acid protein that belongs to the shootin family. The shootin1 protein contains three coiled-coil domains, a proline-rich region and interacts with RUFY3. Shootin1 is involved in the generation of internal asymmetric signals required for neuronal polarization. The shootin1 protein acts upstream of PI3K (phosphoinositide 3-kinase),阅读障碍相关蛋白Shootin抗体  by being required for spatially localized PI3K activity. By accumulating asymmetrically in a single neurite before polarization, shootin1 leads to axon induction for polarization, additionally the absence of shootin1 from the nascent axon's siblings by competition prevents the formation of surplus axons. Existing as seven alternatively 阅读障碍相关蛋白Shootin抗体 spliced isoforms, the shootin1 gene is conserved in chimpanzee, dog, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q25.3.

Also known as:

DKFZp686A0439; hypothetical protein FLJ11122; Kiaa1598; MGC40476; Putative uncharacterized protein KIAA1598; Shootin 1; Shootin-1; Shootin; SHOT1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,阅读障碍相关蛋白Shootin抗体  affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human KIAA1598.

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阅读障碍相关蛋白Shootin抗体 Predicted Molecular Weight: 72kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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