蛋白质精氨酸亚型1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 蛋白质精氨酸亚型1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is 蛋白质精氨酸亚型1抗体involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

蛋白质精氨酸亚型1抗体Also known as:

HPAD10; Padi1; PADI1_HUMAN; PDI; PDI1; Peptidylarginine deiminase I; protein arginine deiminase type I; Protein-arginine deiminase type I; Protein-arginine deiminase type-1.

Specificity:

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Rabbit Polyclonal IgG, 蛋白质精氨酸亚型1抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human PADI1 / PAD1.

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蛋白质精氨酸亚型1抗体Predicted Molecular Weight: 75kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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