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一键询价Quantity size:
0.2ml
Concentration:
1mg/ml 多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint.多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3 Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Tissue specificity: Widely expressed; the highest levels are in the kidney, skeletal muscle, liver, heart and spleen; also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.
多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3Also known as:
hPARP3; IRT1; NAD(+) ADP ribosyltransferase 3; pADPRT 3; Poly[ADP ribose] synthetase 3; ADP ribosyltransferase (NAD+; poly (ADP ribose); ADPRT-3; ADPRT3; ADPRTL2; ADPRTL3; hPARP 3; hPARP-3; IRT 1; IRT1; NAD(+) ADP-ribosyltransferase 3; NAD+ ADP ribosyltransferase 3; pADPRT-3; pADPRT3; PARP 3; PARP-3; PARP3; Poly (ADP ribose) polymerase family, member 3; Poly (ADP ribose) synthetase 3; Poly [ADP-ribose] polymerase 3; Poly[ADP-ribose] synthase 3.
Specificity:
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Rabbit Polyclonal IgG,多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3 affinity purified by Protein A.
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Reacts with: Human, Rat, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human PARP3.
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多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3Predicted Molecular Weight: 60kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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